Project 1: Early-life metal exposure and cognitive aging

The Radiation and Public Health Project

Joe Mangano of the Radiation and Public Health Project is cataloging baby teeth for Project 1. The teeth were originally collected as part of a 1958-1970 study by Washington University in St. Louis, which measured build-up of radioactivity from above-ground atomic bomb test fallout. Project 1 will look at level of metals in the teeth and will re-contact the teeth donors for cognitive evaluation.

Forsyth Institute

Felicitas Bidlack of the Forsyth Institute (leaders in dental and craniofacial research) works with Project 1 on preparation and analysis of the baby teeth samples collected in the 1950s-1970s as part of the St. Louis Baby Tooth study.

McLean Hospital

Laura Germine at McLean Hospital's Laboratory for Brain and Cognitive Health Technology and the McLean Institute for Techology in Psychiatry is developing innovative web-based tools for measuring cognition in Project 1.

Dartmouth College

Project 1's quantification of metals in baby teeth samples are being conducted by Brian Jackson's Trace Element Analysis Core at Dartmouth using laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS).

Harvard T.H. Chan School of Public Health

Our Center is based that the Harvard T.H. Chan School of Public Health where the labs of Marc Weisskopf and David Christiani (Project 1), Quan Lu (Project 2), and Tamarra James-Todd (Community Engagement Core) are located in the Department of Environmental Health. The Research Experience and Training Cordination Core (Susan Korrick) and the Administrative (Quan Lu) and Research Translation Core (Trina von Stackelberg) are also based in the Department of Environmental Health. Brent Coull and Xihong Lin's groups (Data Management and Analysis Core) are in the Department of Biostatistics.